Arthur P Grollman Selected Research

Aristolochic Acids

1/2021	Additive Effects of Arsenic and Aristolochic Acid in Chemical Carcinogenesis of Upper Urinary Tract Urothelium.
1/2016	Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.
1/2015	Aristolochic acid-induced apoptosis and G2 cell cycle arrest depends on ROS generation and MAP kinases activation.
9/2010	Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.
5/2010	Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse.
7/2007	Selective toxicity of aristolochic acids I and II.

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Arthur P Grollman Research Topics

Disease

34	Neoplasms (Cancer) 01/2022 - 02/2005
15	Carcinoma (Carcinomatosis) 01/2022 - 09/2011
7	Chronic Renal Insufficiency 01/2016 - 02/2005
5	Chronic Kidney Failure (Chronic Renal Failure) 07/2016 - 07/2007
4	Carcinogenesis 01/2022 - 08/2003
4	Balkan Nephropathy (Balkan Endemic Nephropathy) 02/2015 - 07/2007
4	Fibrosis (Cirrhosis) 09/2010 - 02/2005
3	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 03/2017
3	Iatrogenic Disease 01/2020 - 01/2013
3	Poisoning 01/2013 - 02/2005
2	Urologic Neoplasms (Urological Cancer) 12/2015 - 01/2013
1	Gout 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 12/2016
1	Neoplasm Metastasis (Metastasis) 07/2016
1	Brain Neoplasms (Brain Tumor) 04/2013
1	Intellectual Disability (Idiocy) 04/2013
1	Melanoma (Melanoma, Malignant) 04/2013
1	alpha-Thalassemia 04/2013
1	Necrosis 07/2007
1	Renal Insufficiency (Renal Failure) 02/2005
1	Hypersensitivity (Allergy) 11/2004
1	Endometrial Neoplasms (Endometrial Cancer) 08/2003
1	Breast Neoplasms (Breast Cancer) 08/2003
1	Xeroderma Pigmentosum (Kaposi's Disease) 02/2002

Drug/Important Bio-Agent (IBA)

24	aristolochic acid I (aristolochic acid)IBA 01/2022 - 02/2005
15	DNA AdductsIBA 01/2021 - 08/2003
11	CarcinogensIBA 01/2022 - 05/2010
10	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 11/2004
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2006
6	Aristolochic AcidsIBA 01/2021 - 07/2007
2	Biological ProductsIBA 03/2017 - 12/2015
1	ChromatinIBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	ArsenicIBA 01/2021
1	N-acetyltalosaminuronic acid (NAT)IBA 07/2016
1	Hazardous Substances (Hazardous Materials)IBA 01/2016
1	Formaldehyde (Formol)FDA Link 12/2015
1	ParaffinIBA 12/2015
1	RNA Splice SitesIBA 08/2013
1	2'-deoxyadenosineIBA 08/2013
1	MutagensIBA 08/2013
1	Plant ExtractsIBA 07/2013
1	Proteins (Proteins, Gene)FDA Link 04/2013
1	Telomerase (Telomerase Reverse Transcriptase)IBA 04/2013
1	Telomere-Binding ProteinsIBA 04/2013
1	Codon (Codons)IBA 09/2011
1	AcidsIBA 01/2010
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2007
1	N 30IBA 02/2005
1	Tamoxifen FDA LinkGeneric 08/2003
1	hydroxide ionIBA 02/2002

Therapy/Procedure

2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2016 - 01/2013
1	Precision Medicine 01/2020
1	Lymph Node Excision (Lymph Node Dissection) 03/2017
1	Neoadjuvant Therapy 03/2017
1	Nephroureterectomy 03/2012
1	Chemoprevention 08/2003